In AD: amyloid beta precursor protein (APP) is located on __.

In AD: amyloid beta precursor protein (APP) is located on __.

Answer: chromosome 21 ( people with trisomy 21 (Down Syndrome) who thus have an extra gene copy almost universally exhibit AD by 40 years of age.)

Damage to __ might relieve the symptoms of PD.

Damage to __ might relieve the symptoms of PD.

Answer: GPi (Globus Pallidus Internal)

Nigrostriatal Pathway: ___ channels regulate spontaneous activity of DA cells in NGS pathway.

Nigrostriatal Pathway: ___ channels regulate spontaneous activity of DA cells in NGS pathway.

Answer: Ca2+ channels

__ of cases of PD are sporadic (occur in the absence of family history).

__ of cases of PD are sporadic (occur in the absence of family history).

Answer: 95%